Hemoglobin D/B+ Compound Heterozygote with Autoimmune Hemolytic Anemia

Unaiza Qamar, Nisar Ahmed

Abstract


A 10 years old child presented with progressive pallor since birth and history of jaundice and abdominal distension since 4 months.Investigations revealed a positive Direct antiglobulin test and a diagnosis of Autoimmune hemolytic anemia was made.Steroids were given and patient responded to it as per laboratory investigations and alleviation of jaundice, but clinically pallor persisted.Hemoglobin Electrophoresis revealed a significant percentage of Hb D and A2, suggestive of HbD/B+ trait that was later confirmed by parents’ screening.

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