Evaluation of left ventricular diastolic function by tissue doppler imaging after acute myocardial infarction

Abstract

Background: Diastolic dysfunction has been recognized during the early and the post myocardial infarction phase. The aim of this study was to evaluate the left ventricular diastolic function by Tissue doppler imaging after acute myocardial infarction.

Material & Methods: It was a descriptive study, from 1st July 2010 to 31st December 2010. Total of 200 patients having acute myocardial infarction underwent detailed tissue Doppler imaging echocardiographic examination for evaluation of left ventricular diastolic function on day 3, in echocardiographic section, LRH, Peshawar. Data was analyzed Using SPSS version 16.

Results: The sample volume was divided into 4 groups i.e. anterior MI, inferior MI, septal MI, and lateral MI. There were 122 males and 78 females and the mean age was 42 ± 5.0 years. Peak early diastolic (Em) and peak late diastolic (Am) velocities were recorded at 4 different sites of the mitral annulus. Em velocity was reduced, especially at the infarction sites. The mean peak early diastolic velocity from 4 mitral annulus sites was well correlated with ejection fraction (p=0.0001). While the mean Em velocity showed negative correlation with mitral inflow early velocity (E) and also with early to late velocity ratio (E/A). The mean Em velocity was correlated well with isovolumic relaxation time. There was no correlation between mean Em velocity and deceleration time.

Conclusion: Tissue Doppler Imaging is a reliable mode of echocardiography for assessment of left ventricular diastolic functions.