NAVIGATING THE CHALLENGES OF HEPATOBILIARY OBSTRUCTION IN HEPATOCELLULAR CARCINOMA RESECTION: A REVIEW OF CURRENT EVIDENCE

Tauqeer Muhammad; Huang Xue; Jiang Li

doi:10.46903/gjms/23.3.1995

NAVIGATING THE CHALLENGES OF HEPATOBILIARY OBSTRUCTION IN HEPATOCELLULAR CARCINOMA RESECTION: A REVIEW OF CURRENT EVIDENCE

Tauqeer Muhammad, Huang Xue, Jiang Li

Abstract

Hepatocellular carcinoma (HCC) is a leading cause of cancer-related mortality worldwide, with surgical resection as a primary healing method. However, hepatobiliary obstruction (HBO) gives a good-sized assignment, regularly complicating perioperative management and long-term consequences. This review critically examines the pathophysiology of HBO in HCC, its effect on surgical feasibility, and the modern advancements in diagnostic and therapeutic techniques. We discuss the role of biliary decompression strategies, including percutaneous transhepatic biliary drainage (PTBD) and endoscopic biliary stenting, in optimizing surgical candidacy and enhancing postoperative restoration. Furthermore, we compare emerging approaches, along with neoadjuvant treatment plans and minimally invasive surgical techniques, in mitigating HBO-related complications. Despite advancements, HBO remains a main prognostic determinant, necessitating an interdisciplinary method to improve surgical success and patient survival. Future studies have to be aware of refining danger stratification models and integrating novel biomarkers to enhance early detection and individualized treatment strategies.

Keywords

Decompression; Drainage; Hepatocellular carcinoma; Obstruction; Resection; Stenting.

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DOI: https://doi.org/10.46903/gjms/23.3.1995