COMPARATIVE EFFICACY OF DEXAMETHASONE VERSUS EVENING PRIMROSE OIL ON BISHOP SCORE AND DEVELOPMENT OF LABOUR IN POSTDATE PREGNANCY

Shaimaa Abdulamer Nasir

Abstract


Background: The postdate pregnancy is an obstetric problem . we need to enhance cervical preparation prior to induced labour which is needed to decrease maternal and fetal morbidities .this can be achieved by many ways. The determination of this research stayed to examine the efficiency and protection of using vaginal primrose oil capsules versus intravenous dexamethasone for cervix preparation and induced labor duration in full-term pregnancies.

Materials & Methods: It was a randomized case control study started from November 2023 to June 2024, 84 primiparous females with a gestational age of 40-42 weeks and a Bishop Score of 4 or fewer stood confessed to the obstetrics and Gynecology Department at Al Diwanyiah maternity and children teaching hospital to terminate their pregnancies. The study sample 84 calculated with convidence level 80% and margin of error 5%. Simple random method used to select and divided the sample into three groups, 30 people were given 8 milligrams of intravenous dexamethasone, 29 people were given one evening primrose oil capsule vaginally, and 25 people as a control. All of them were given 6 hours before induction. Then we induce labor with oxytocin and then compare the three groups regarding labour progress and the neonatal outcome.

Results: Results show that after 6 hours of injecting dexamethasone, there is a statistical alteration in the Bishop scoring system among the two groups (5.88±1.18, vs. 5.19±0.85 correspondingly). In the dexamethasone grouping, the time it took to go as of the start of initiation to the start of the vigorous labor stage stayed 90±26.3 minutes, which is shorter than in the controlling group’s 112.88±48.87 minutes. The initial and second stages of labor are completed more quickly in the group of dexamethasone paralleled to the controlling grouping.

Conclusions: Dexamethasone’s administration may contribute more significantly to the process of cervical ripening and labor advancement compared to primrose oil.


Keywords


Dexamethasone; primrose oil; Bishop Score; Initiation of labor; phases of labor; Cervical ripening.

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References


Mohaghegh Z, Faal Siahkal S, Bahmaei H. The effect of dexamethasone on labor induction: a systematic review. BMC Pregnancy Childbirth. 2021;21:563. https://doi.org/10.1186/s12884-021-04010-1

Bellussi F, Seidenari A, Juckett L, Di Mascio D, Berghella V. Induction within or after 12 hours of ≥36 weeks' prelabor rupture of membranes: a systematic review and meta-analysis. Am J Obstet Gynecol MFM. 2021;3(5):100425. https://doi.org/10.1016/j.ajogmf.2021.100425

Salman MM, Salama FA, Yacoub M, Elkady M. Intravenous dexamethasone versus vaginal misoprostol in enhancing cervical ripening and labor induction. Acta Gynecol Obstet. 2022;14:12-17. https://doi.org/10.1093/qjmed/hcab115.021

Foda A, Shata A, El-Said Z. Glucocorticoids shorten and speed up the misoprostol-induced labour in postdate pregnancy. Benha Med J. 2023;40(3):759-763. https://doi.org/10.21608/bmfj.2023.210333.1814

Farahani M, Nirouei M, Moghadam S, Hashemnejad M, Mashak B, Alinia T, et al. The effect of using dexamethasone tablets vaginally for improving cervical Bishop score in nulliparous pregnant women: a randomized clinical trial. Curr Ther Res Clin Exp. 2023;98:100702. https://doi.org/10.1016/j.curtheres.2023.100702

Shabanian S, Danesh A, Najafi S. Investigating the effect of hyoscine and dexamethasone on cervical preparation in primigravid women with term pregnancy: a double-blind randomized clinical trial. J Res Pharm Pract. 2024;12(4):130-134. https://doi.org/10.4103/jrpp.jrpp_41_24

Hemmatzadeh S, Ahmadpoor P, Kamrani S, Mirghafourvand M. Effect of dexamethasone on labour induction and cervical ripening in term pregnancies: a systematic review and meta-analysis. J Obstet Gynaecol. 2022;42(6):1669-1678. https://doi.org/10.1080/01443615.2022.2069001

Saleh Zaher T, Gharib M, El Saied A, Amin A. Role of dexamethasone on cervical ripening and induction of labor in term pregnancy. Zagazig Univ Med J. 2021;27(6):1518-1523. https://doi.org/10.21608/zumj.2019.17069.1526

Hajivandi L, Montazeri S, Iravani M, Haghighizade M. The effects of intramuscular dexamethasone on cervical ripening and induction of labor. Pars J Med Sci. 2022;11(3):11-16. https://doi.org/10.29252/jmj.11.3.11

Heydari P, Azizi F, Khakbazan Z, Geranmayeh M. Comparing the effects of vaginal and oral evening primrose oil on cervical ripening and labor progress among primiparous women. Nurs Pract Today. 2022;9(3):234-242. https://doi.org/10.18502/npt.v9i3.10225

Wafa YA, Zakaria AM, Rizk YHA. Efficacy of dexamethasone on latent phase during induction of labour. Al-Azhar Int Med J. 2023;4(12):164-171. https://doi.org/10.58675/2682-339X.2179

Sahar S, Firdous T, Alia A, Manzoor N. Extra-amniotic infusion of corticosteroids versus normal saline for cervical ripening and shortening of 1st stage of labour in mid-trimester termination of pregnancy. Pak J Med Health Sci. 2022;16(12):782-785. https://doi.org/10.53350/pjmhs20221612782

Mokhtarpour S, Sahhaf F, Vahedi L, Sani A. Evaluation of mechanical and nonmechanical methods of cervix ripening in women with pre-labor rupture of membranes: a randomized controlled trial. Am J Obstet Gynecol MFM. 2023;5(4):100868. https://doi.org/10.1016/j.ajogmf.2023.100868

Sammour H, Ashoush S, Elhawwary G, Rekaby S. Effect of intramuscular administration of dexamethasone on shortening of the duration of induction of labor. QJM. 2021;114(1):hcab115.034. https://doi.org/10.1093/qjmed/hcab115.034

Lassey SC, Haber HR, Kanbergs A, Robinson JN, Little SE. Six versus twelve hours of single-balloon catheter placement with oxytocin administration for labor induction: a randomized controlled trial. Am J Obstet Gynecol. 2021;224(6):611.e1-611.e8. https://doi.org/10.1016/j.ajog.2021.03.021




DOI: https://doi.org/10.46903/gjms/23.1.1843

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