HISTOPATHOLOGICAL SPECTRUM OF OVARIAN LESIONS UNDERGOING SURGICAL MANAGEMENT IN A TERTIARY CARE HOSPITAL, AN OBSERVATIONAL STUDY

Nazish Hayat; Samdana Wahab; Faryal Abid; Sania Azmat; Mahrukh Azmat; Aneela Rafiq

doi:10.46903/gjms/22.02.1598

HISTOPATHOLOGICAL SPECTRUM OF OVARIAN LESIONS UNDERGOING SURGICAL MANAGEMENT IN A TERTIARY CARE HOSPITAL, AN OBSERVATIONAL STUDY

Nazish Hayat, Samdana Wahab, Faryal Abid, Sania Azmat, Mahrukh Azmat, Aneela Rafiq

Abstract

Background: Ovarian cysts affect 7% of women worldwide. Many resolve spontaneously, while a significant number end up in surgery. Histopathological type is used for the final diagnosis of these cysts. The objective of this study was to find out the frequency of various histopathological types of ovarian cysts undergoing surgical management in Lady Reading Hospital, Peshawar.

Materials & Methods: A retrospective observational study was conducted in the Obstetrics and Gynaecology Department of Lady Reading Hospital, Peshawar after approval from the Institutional Ethical Research Committee. About 4 years (January 2020 till December 2023), statistical data of all patients undergoing surgical removal of ovarian cysts was retrieved from Health Management Information System (HMIS). Cases of para ovarian cysts and already diagnosed cases of malignant ovarian cysts were excluded. Data was entered on SPSS version 26. Frequencies and percentages for categorical variables, Mean and standard deviation numerical variables were used.

Results: Total 229 cases were included. The mean age of patients was 31.71±10.60. Bilateral cysts occurred in 19 patients. On histopathological diagnosis, mature cystic teratoma occurred in 24.5%, endometriotic cysts in 22.7%, and serous cystadenomas in 18.3% of cases. Based on size, mucinous cysts were larger with overall diameters of 16.8cm ±6.6cm. About 7.8% of cysts were associated with torsion, 2% with ascites, and 1.7% with metastasis. The association of age more than 50 years was noted with risk of malignancy. No significant size difference in benign and malignant counter parts was noted.

Conclusion: Mature cystic teratomas were the most frequent histological type of ovarian cyst, followed by endometriotic cysts. Increasing age was found significantly associated with risk of malignancy.

Keywords

Ovarian cysts; epithelial ovarian cancer; corpus luteum cyst; classification; surgical procedure.

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DOI: https://doi.org/10.46903/gjms/22.02.1598