KNOWLEDGE,ATTITUDE, AND PRACTICE OF HEALTH-CARE PROFESSIONALS REGARDING ADVERSE DRUG REACTION REPORTING IN SELECTED PEDIATRIC HOSPITALS IN KURDISTAN/ IRAQ

Bootan A. Salih; Omer Allela

doi:10.46903/gjms/22.01.1542

KNOWLEDGE,ATTITUDE, AND PRACTICE OF HEALTH-CARE PROFESSIONALS REGARDING ADVERSE DRUG REACTION REPORTING IN SELECTED PEDIATRIC HOSPITALS IN KURDISTAN/ IRAQ

Bootan A. Salih, Omer Allela

Abstract

Background: Adverse drug reactions (ADRs) are one of the major challenges in healthcare settings, especially in pediatric hospitals where children are more vulnerable to drug effects. This study aimed to assess the knowledge, attitude, and practice (KAP) of healthcare professionals regarding ADR reporting and identify factors associated with increased reporting.

Materials & Methods: A cross-sectional study design was conducted on a total of 401 healthcare professionals which were sampled by convenience method and data collected by interview to assess their KAP using a structured questionnaire.

Results: The total knowledge scores were highest among pharmacists (21.0 ±4.3) compared to nurses (15.0 ±4.6) and physicians (17.4 ±4.6) (p<0.001). Similar patterns were noted for attitudes and practices. Higher KAP scores were significantly associated with increased ADR reporting.

Conclusion: The finding of this study showed that the KAP of the Healthcare providers towards spontaneous ADR reporting were low. Awareness among Healthcare providers, collaboration among other healthcare professionals and training for healthcare providers were the highly suggested ways to improve ADR reporting.

Keywords

Adverse Drug Reaction reporting; healthcare practioners; Pharmacists; pediatric; Iraq.

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References

Pharmacovigilance: Ensuring the Safe Use of Medicines- WHO Policy Perspectives on Medicines, No. 009, October 2004 [Accessed 14th September 2015] Available from: http://apps.who.int/medicinedocs/en/d/Js6164e/

Guidelines for Detecting & Reporting Adverse Drug Reactions: Individual Case Safety Reports for Healthcare Professionals, Rational Drug Use and Pharmacovigilance Department- JFDA,2014.

World Health Organization, "International drug monitoring: the role of national centers," Technical Report Series 498, World Health Organization, Geneva, Switzerland, 1972.

George C, Nathanson V, Seddon C, Jayesinghe N, Jackson G, Chen E, et al. Reporting adverse drug reactions: a guide for healthcare professionals. BMA Board of Science. 2006.

Kurokawa T, Correa-Nunes AM, Czarnecki A, et al. Safety Monitoring of Medicinal Products: Guidelines for Setting up and Running a Pharmacovigilance Centre. The Uppsala Monitoring Centre (the UMC), WHO Collaborating Centre for International Drug Monitoring; 2000.

Abubakar AR, Simbak NB, Haque M. A systematic review of knowledge, attitude and practice on adverse drug reactions and pharmacovigilance among doctors. J Appl Pharm Sci. 2014;4(10):117-27. https://doi.org/10.7324/JAPS.2014.401021

Ishiguro C, Hall M, Neyarapally GA, Dal Pan G. Post-market drug safety evidence sources: an analysis of FDA drug safety communications. Pharmacoepidemiol Drug Saf 2012;21(10):1134-36. https://doi.org/10.1002/pds.3317

Stricker BC, Psaty BM. Detection, verification, and quantification of adverse drug reactions. Br Med J 2004;329(7456):44-7. https://doi.org/10.1136/bmj.329.7456.44

Teshale C, Melaku R. Attitude and practice of health professionals towards adverse drug reaction (ADR) reporting in Jimma Zone hospitals, Southwest Ethiopia. Pharmacol Online 2010;2:308-15.

Mulatu WN, Worku A. Assessment of knowledge, attitude and practice of health professionals towards adverse drug reaction reporting and factors associated with reporting. J Pharmacovigil. 2014;2(4):1-7. http://dx.doi.org/10.4172/2329-6887.1000135

Abdel-Latif MMM, Abdel-Wahab BA. Knowledge and awareness of adverse drug reactions and pharmacovigilance practices among healthcare professionals in Al-Madinah Al Munawwarah, Kingdom of Saudi Arabia. Saudi Pharm J 2015;23(2):154-61. https://doi.org/10.1016/j.jsps.2014.07.005

Bharadwaj V, Budania N, Mondal A, Yadav V, Sharma P. A survey to assess the awareness of adverse drug reactions and pharmacovigilance practices among healthcare professionals in a tertiary care hospital. Int J Med Res Prof 2016;2(1):134-7.

Al-Hazmi N, Naylor IL. Attitude and awareness of adverse drug reaction reporting by health professionals in seven hospitals in the Holy City of Makkah, Kingdom of Saudi Arabia. Clin Trials. 2013;3:3. https://doi.org/10.4172/2167-0870.1000139

Suyagh M, Farah D, Abu Farha R. Pharmacist's knowledge, practice and attitudes toward pharmacovigilance and adverse drug reactions reporting process. Saudi Pharm J 2015; 23: 147-53. https://doi.org/10.1016/j.jsps.2014.07.001

Kohli S, Tayal R, Goyal T. Antihistamines in children: A dermatological perspective. Indian J Paediatr Dermatol. 2022;23(1):8. https://doi.org/10.4103/ijpd.ijpd_124_21

Kadir A, Shenoda S, Goldhagen J. Effects of armed conflict on child health and development: a systematic review. PLoS One. 2019;14(1):e0210071. https://doi.org/10.1371/journal.pone.0210071

Alshammari TM, Mendi N, Alenzi KA, Alsowaida Y. Pharmacovigilance systems in Arab countries: overview of 22 Arab countries. Drug Saf 2019;42(7):849-68. https://doi.org/10.1007/s40264-019-00807-4

Fadare JO, Enwere OO, Afolabi AO, Chedi BAZ, Musa A. Knowledge, attitude and practice of adverse drug reaction reporting among healthcare workers in a tertiary centre in Northern Nigeria. Trop J Pharm Res. 2011;10(3):235-42. https://doi.org/10.4314/tjpr.v10i3.4

Palaian S, Ibrahim MI, Mishra P. Health professionals' knowledge, attitude and practices towards pharmacovigilance in Nepal. Pharmacy Pract 2011;9(4):228-35. https://doi.org/10.4321/S1886-36552011000400008

Angamo MT, Tesfa A, Wabe NT. Knowledge, attitude and practice of adverse drug reaction reporting among health professionals in southwest Ethiopia. TAF Prev Med Bull 2012;11(4):397-406. https://doi.org/10.5455/pmb.1-1313732484

"Report on the assessment of health care providers' knowledge, attitude and practice on Adverse Drug Reaction (ADR) reporting and its monitoring: Drug Administration and Control Authority in collaboration with MSH/RPM plus/SPS," 2008.

Gupta SK, Nayak RP, Shivaranjani R, Vidyarthi SK. A questionnaire study on the knowledge, attitude, and the practice of pharmacovigilance among the healthcare professionals in a teaching hospital in South India. Perspect Clin Res 2015;6(1):45-52. https://doi.org/10.4103/2229-3485.148816

Inman WH. Attitude to adverse drug reaction reporting. Br J Clin Pharmacol 1996;41:433-435. https://doi.org/10.1111/j.1365-2125.1996.tb00040.x

Gupta P, Udupa A. Adverse drug reaction reporting and pharmacovigilance: Knowledge, attitudes and perceptions amongst resident doctors. J Pharm Sci Res. 2011;3(2):1064-1069.

DOI: https://doi.org/10.46903/gjms/22.01.1542