SEVERITY OF RECENTLY DIAGNOSED PRIMARY GLAUCOMA AT PRESENTATION IN KHYBER PAKHTUNKHWA
Abstract
Background: Glaucoma is a progressive optic neuropathy with distinct visual field defects. The aim of this study was to determine the severity at presentation of recently diagnosed primary glaucoma.
Materials & Methods: This observational cross-sectional study was conducted at the Glaucoma clinic of Department of Ophthalmology, Hayatabad Medical Complex, Peshawar from July 2023 to February 2024. After obtaining the ethical approval, patients of primary open angle glaucoma (POAG) and primary angle closure glaucoma (PACG) who were recently diagnosed (i.e. in last six months) were included in this study. All the patients underwent comprehensive ocular examination including intraocular pressure (IOP) measurement, gonioscopy and standard automated perimetry. The severity of glaucoma was determined by using the visual field parameters of Hoddap-Parrish-Anderson criteria. The demographics of both groups were recorded, and severity was determined by analysis through SPSS version 26.
Results: A total 228 eyes of 114 patients or primary glaucoma were included. Of these 114 patients, 57 were included in each group; Primary Open Angle Glaucoma (POAG) in group A and Primary Angle Closure Glaucoma (PACG) in group B. Group A had a mean age of 48.3 ±10.6 years while Group B had a mean age of 50.8 ± 11.9 years. In group A , the glaucoma was mild in 11 (19.3%) patients, moderate in 32 (56.1%) and severe in 14 (24.6%) patients. In group B, the glaucoma was mild in 15 (26.3%) patients, moderate in 33 (57.9%) and severe in 9 (15.8%) patients.
Conclusion: Majority of primary glaucoma patients present with moderate to severe stage of glaucoma at the time of initial diagnosis.
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Lin Y, Jiang B, Cai Y, Luo W, Zhu X, Lin Q, et al. The global burden of glaucoma: findings from the Global Burden of Disease 2019 study and predictions by Bayesian age-period-cohort analysis. J Clin Med. 2023;12(5):1828. https://doi.org/10.3390/jcm12051828
Kazmi S, Jabeen A, Gul R. Rising glaucoma burden in Pakistan: a wake-up call for nationwide screening? J Pak Med Assoc. 2022 May;72(5):1016. https://doi.org/10.47391/JPMA.3722. PMID: 35713085.
Stein JD, Khawaja AP, Weizer JS. Glaucoma in adults-screening, diagnosis, and management: a review. JAMA. 2021;325(2):164-74. https://doi.org/10.1001/jama.2020.21899
Zhang N, Wang J, Chen B, Li Y, Jiang B. Prevalence of primary angle closure glaucoma in the last 20 years: a meta-analysis and systematic review. Front Med. 2021 Jan 18;7:624179. https://doi.org/10.3389/fmed.2020.624179
George R, Panda S, Vijaya L. Blindness in glaucoma: primary open-angle glaucoma versus primary angle-closure glaucoma-a meta-analysis. Eye. 2022 Nov;36(11):2099-105. https://doi.org/10.1038/s41433-021-01802-9
Hamid S, Desai P, Hysi P, Burr JM, Khawaja AP. Population screening for glaucoma in UK: current recommendations and future directions. Eye. 2022 Mar;36(3):504-9. https://doi.org/10.1038/s41433-021-01687-8
Alwazae M, Alhumud A, Aldarrab A, Hemid AB, AlHassan RA, AlAdel F, et al. Encounter glaucoma decision aid trial. Eur J Ophthalmol. 2023 Jan;33(1):291-6. https://doi.org/10.1177/11206721221093020
Arshad H, Ali M, Khan AS, Akhtar F, Mueed A. Late presentation of primary open-angle glaucoma and its predictors at a tertiary eye care hospital in Pakistan. J Clin Exp Ophthalmol. 2021;12:899.
Hodapp E, Parrish RK II, Anderson DR. Clinical decisions in glaucoma. St. Louis, MO: C.V. Mosby; 1993.
Sadiq M, Mahsood YJ, Ahmad W, Khan MA, Akhtar F. Demographic and socioeconomic characteristics of glaucoma suspects in a tertiary care center of Pakistan. Pak J Ophthalmol. 2023;39(1):55-60. https://doi.org/10.36351/pjo.v39i1.1499
De Moraes CG, Liebmann JM, Levin LA. Detection and measurement of clinically meaningful visual field progression in clinical trials for glaucoma. Prog Retin Eye Res. 2017 Jan;56:107-47. https://doi.org/10.1016/j.preteyeres.2016.10.001
Bhedasgaonkar S, Nadkarni SU. Extent of glaucomatous damage on the first presentation. Oman J Ophthalmol. 2023 May 1;16(2):227-32. https://doi.org/10.4103/ojo.ojo_51_22
El-Medany AY, Jeganathan VS, Tatham AJ. Severity of glaucoma at first presentation to hospital eye services. Int J Open Access Ophthalmol. 2017;2(1):1-5. https://doi.org/10.15226/2474-9249/2/1/00122
Mahabadi N, Zeppieri M, Tripathy K. Open-angle glaucoma. In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2024 Jan-. PMID: 28722917.
Kapetanakis VV, Chan MP, Foster PJ, Cook DG, Owen CG, Rudnicka AR. Global variations and time trends in the prevalence of primary open-angle glaucoma (POAG): a systematic review and meta-analysis. Br J Ophthalmol. 2016;100(1):86-93. https://doi.org/10.1136/bjophthalmol-2015-307223
Tan C, Hou Y, Qiao YS, Chen JY, Sun XH. The study of the correlation between age and the pathogenic factors of primary glaucoma: a review. Zhonghua Yan Ke Za Zhi. 2022 Dec;58(12):1106-10. https://doi.org/10.3760/cma.j.cn112142-20220616-00297
Kim HJ, Sung MS, Park SW. Factors associated with visual acuity in advanced glaucoma. J Clin Med. 2023 Apr 24;12(9):3076. https://doi.org/10.3390/jcm12093076
Lee BL, Wilson MR; Ocular Hypertension Treatment Study (OHTS). Ocular Hypertension Treatment Study (OHTS) commentary. Curr Opin Ophthalmol. 2003 Apr;14(2):74-7. https://doi.org/10.1097/00055735-200304000-00003
Sekimitsu S, Elze T, Zebardast N. Impact of the Affordable Care Act on glaucoma severity at first presentation. Ophthalmic Epidemiol. 2023 Jun;30(3):326-9. https://doi.org/10.1080/09286586.2022.2089357
Gedde SJ, Vinod K, Wright MM, Muir KW, Lind JT, Chen PP, et al. American Academy of Ophthalmology Preferred Practice Pattern Glaucoma Panel. Primary open-angle glaucoma preferred practice pattern®. Ophthalmology. 2021 Jan;128(1):71-150. https://doi.org/10.1016/j.ophtha.2020.10.022
DOI: https://doi.org/10.46903/gjms/22.4.suppl.1745
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